2019年3月18日星期一

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sorafenib tosylate_[PDF]Draft Guidance on Sorafenib Tosylate

Draft Guidance on Sorafenib Tosylate This draft guidance, once finalized, will represent the Food and Drug Administration's (FDA's) current thinking on this topic.

sorafenib tosylate_Sorafenib tosylate - DrugBank

Sorafenib tosylate Drug Entry Sorafenib. Sorafenib (rINN), marketed as Nexavar by Bayer, is a drug approved for the treatment of advanced renal cell carcinoma (primary kidney cancer).

sorafenib tosylate_Sorafenib - Wikipedia

Sorafenib (co-developed and co-marketed by Bayer and Onyx Pharmaceuticals as Nexavar), is a kinase inhibitor drug approved for the treatment of primary kidney cancer (advanced renal cell carcinoma), advanced primary liver cancer (hepatocellular carcinoma), FLT3-ITD positive AML and radioactive iodine resistant advanced thyroid carcinoma.

sorafenib tosylate_Sorafenib Tablet - WebMD

Sorafenib is used to treat kidney, liver, and thyroid cancer. It is a chemotherapy drug that works by slowing or stopping the growth of cancer cells.

sorafenib tosylate_Sorafenib Tosylate|Bay 43-9006|CAS 475207-59-1 Buy ...

Sorafenib tosylate is a potent multikinase inhibitor, with IC 50 s of 6 nM, 20 nM, and 22 nM for Raf-1 , B-Raf , and VEGFR-3 , respectively....Quality confirmed by NMR,HPLC & MS.

sorafenib tosylate_Sorafenib Tosylate - Buy Sorafenat 200mg Tablets Rs-1 ...

Sorafenib Tosylate Tablets are available under the brand name of sorafenat 200 mg Tablets. Sorafenib Tosylate comes in 200 mg tablets form. Sorafenat (sorafenib) is a cancer (chemotherapeutic) medication.

sorafenib tosylate_Sorafenib Tosylate | CAS 475207-59-1 | SCBT - Santa Cruz ...

Sorafenib Tosylate is an inhibitor of c-Kit, Flk-1, Flt-3/Flk-2, Flt-4, PDGFR-β, Raf-1 and Raf-B.

User rating: 5/5sorafenib tosylate_Sorafenib Tosylate|Raf kinases and tyrosine kinases ...

Sorafenib tosylate, also named nexavar, is a small-molecule anticancer compound [1]. It is also a novel oral Raf kinase and a vascular endothelial growth factor receptor (VEGFR) inhibitor. It inhibits tumor cell proliferation and tumor angiogenesis [2].

sorafenib tosylate_Sorafenat (Sorafenib Tosylate) - 200mg (120 Tablets ...

Sorafenib (Sorafenat) is a new medicine used to treat a type of liver cancer called hepatocellular carcinoma, especially in cases where the cancer cannot be surgically removed. It can also be used to treat advanced renal cell carcinoma (a type of kidney cancer) and some cases of thyroid cancer.

sorafenib tosylate_Sorafenib Tosylate With or Without Stereotactic Body ...

Sorafenib Tosylate With or Without Stereotactic Body Radiation Therapy in Treating Patients With Liver Cancer The safety and scientific validity of this study is the responsibility of …

sorafenib tosylate_WO2009054004A2 - Process for the preparation of sorafenib ...

A novel and improved process for the preparation of sorafenib (4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-methylpicolinamide) of formula (I) involving a novel intermediate of formula (II) as key intermediate is disclosed. Sorafenib tosylate, available in the market as Nexavar is a multiple kinase inhibitor targeting both RAF kinase and receptor tyrosine kinase that …

sorafenib tosylate_Material Safety Data Sheet of Sorafenib Tosylate | AbMole ...

Material Safety Data Sheet of Sorafenib Tosylate contains identification of substance and details of the supplier of the safety data sheet.

sorafenib tosylate_[PDF]HIGHLIGHTS OF PRESCRIBING INFORMATION These …

Tablets containing sorafenib tosylate (274 mg) equivalent to 200 mg of sorafenib. NEXAVAR tablets are round, biconvex, red film-coated tablets, debossed …

sorafenib tosylate_Bevacizumab, sorafenib tosylate, sunitinib and ...

Sorafenib tosylate and sunitinib compared with best supportive care as second-line therapy We were unable to locate any comparative trials of sunitinib as second-line therapy in this population. The PenTAG model estimated a cost per QALY for sorafenib versus best supportive care of £102,498.



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